iron depletion produced large decrease in IR compared with nutrition counseling alone,independent of change in BMI

「BMIの変化に関係なく、栄養指導だけと比べ鉄減少はIRの
大きな減少を導いた」

でいいでしょうか??
compared withが何を比較しているかわかりません・・・・

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A 回答 (1件)

 Role of hepatic iron in non-alcoholic steatohepatitisを読んでいるのでしょうが、IRが何の略語が分かりますか?


 まさか、医学部の学生さんではないですよね。

Non-alcoholic fatty liver disease (NAFLD) includes a spectrum of clinical entities ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) with possible evolution to cirrhosis and hepatocellular carcinoma. Iron is considered a putative element that interacts with oxygen radicals in inducing liver damage and fibrosis. The role of hepatic iron in the progression of NASH remains controversial, but in some patients, iron may have a role in the pathogenesis of NASH. Though genetic factors, insulin resistance, dysregulation of iron-regulatory molecules, erythrophagocytosis by Kupffer cells may be responsible for hepatic iron accumulation in NASH, exact mechanisms involved in iron overload remain to be clarified. Iron reduction therapy such as phlebotomy or dietary iron restriction may be promising in patients with NASH/NAFLD to reduce insulin resistance as well as serum transaminase activities.

この回答への補足

医学部ではないです!!
IRはインスリン抵抗性だとわかるのですが・・・

補足日時:2009/05/17 20:26
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